Mark Russinovich, a Microsoft Technical Fellow, presented a very good session at the TechEd IT Forum last year on the topic of advanced eradication of malware on Windows machines. It's a great session and has some useful advanced techniques for removal. It is also a very good resource for those who want to better understand how malware infects and what some of the risks are. Lots of practical information and how-to's in this one.

Fortunately, the session was recorded and is available online for anyone who wants to see it. If viruses and malware are a part of your job or if this type of security topic is of interest to you, it's an hour and twelve minutes well-spent. I went looking for this session online hoping to find the PowerPoint and found the whole session with video and demo and everything - terrific stuff.

(Updated 4/7 - link to video fixed)